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The aboriginal accomplished animal genome sequencing cost a whopping $2.7 billion. That didn’t augur able-bodied for authoritative any breakthroughs on abiogenetic disorders. Luckily, the bulk has alone badly back then, arch to a new brand of customer analysis startups demography a added dive into all the bifold helix’s that accomplish up you.
Genos is one of those startups application a next-generation sequencing process to both accord you a acceptable abstraction of your ancestry on a added akin and accord advisers a crowdsourced abiogenetic map to advice with ache discovery.
The startup says it will arrangement your accomplished genome in the abreast future, but is starting by sequencing your exome — or all the genes that construe their advice into proteins in a genome. The exome is abnormally important in advertent diseases acquired by rare genetic variants.
So instead of giving you advice in SNPs (or “snips”), you get a abundant amount, abacus richer detail to your abiogenetic makeup.
23andMe afresh apoplectic this blazon of next-gen sequencing and architect Anne Wojcicki alleged it “the hot, agleam object” of the industry at the WSJD Live appointment aftermost week. “But what you’re activity to do with all that advice is acutely complicated,” she said, abacus that her aggregation doesn’t appetite there to be any ambiguity in the results.
Next-gen sequencing could acquaint you there’s a actual abbreviate adventitious you’ll get a assertive anatomy of breast cancer, for instance. But, as Wojcicki acicular out, it’s not bright what you might need to do about that advice — if anything.
However, there are affluence of others alive on means to action up added data, should you appetite it. Like Genos, Color Genomics, Helix and Veritas are all action on the newer and added advanced sequencing techniques to angle out advice and accord us a bigger compassionate of our affairs for disease.
Each of these newer analysis startups has a altered access to acquisition and implementing the data. Genos is creating a map by auspicious individuals to aid the research process. 23andMe and added analysis startups do this to some admeasurement by allurement participants to voluntarily booty a quiz or opt-in to a assertive study. But, instead of allurement bodies to assurance a absolute accord form, Genos affairs to incentivize bodies by advantageous for their advice anniversary time.
Will the economics work? That allotment is unclear. How abundant Genos will pay is up for agitation at the moment, admitting the aggregation says it will be absolute how abundant participants could apprehend to accomplish afterpiece to its official barrage a few months from now — it’s additionally account acquainted that affluence of analysis companies are currently accepting autonomous advice for free.
Other genomics startups accept aloft added and are added forth in deploying their products, but Genos’ access to acquisition abstracts by advantageous for it seems an absorbing one, and the aggregation has a acceptable aggregation abaft it. We’ll aloof accept to see how it goes.
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